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Writer's pictureMaryland Connoisseur

Isana Genetics: Crafting Legacy Through Heritage, Innovation, and Terpene-Driven Cannabis

Updated: Nov 27

In the heart of Maryland’s cannabis scene, Isana Genetics stands as a unique bridge between the past and future of cannabis cultivation. Founded by partners Brent Guyton and Kevin Palma, who share decades of experience and a deep passion for the plant, Isana Genetics is all about combining heritage cannabis genetics with cutting-edge innovation. This article explores their journey, philosophy, and the meticulous breeding process that has allowed Isana Genetics to stand out in an increasingly competitive market.


Brent, co-founder of Isana Genetics, wearing glasses and a black hoodie with the Isana logo, stands next to Kevin, his co-founder, who is wearing a red jacket, at the Maryland Leaf holiday party with friends.

As a cannabis photographer, I’ve always believed that the smallest details can tell the biggest stories. Whether it’s capturing the frost on a bud or the vibrant pistils, my goal is to bring out the essence of the plant. Talking with Brent and Kevin, I realized they share this philosophy in their breeding approach, where the nuances of aroma, flavor, and structure come together to create cannabis that resonates with connoisseurs and newcomers alike.


Balancing Tradition and Innovation in Cannabis


Brent and Kevin’s approach to cannabis cultivation stems from years of working with older cultivars. They both were curious about how their seasoned genetics would interact with newer strains emerging in today’s market. The COVID-19 pandemic, while a challenging period, created opportunities for them to acquire new genetics and experiment with blending the old and new. This blend allows them to maintain authenticity while pushing the boundaries of what cannabis can be. “Creativity & COVID!” Brent shares.


“Having worked the older cultivars for years, we were both curious about how our seasoned cultivars would grow and perform with these newer genetics. The balance for us is staying authentic to the plant and ourselves.”

While some of the newer plant structures may look unfamiliar, Brent and Kevin have found ways to identify and nurture the strains that truly resonate as “cannabis.”


Extreme close-up of cannabis pistils and trichomes on a purple-hued bud from Isana Genetics, showcasing intricate details and frosty resin glands, ideal for cannabis branding and connoisseur appeal.

The Role of Terpenes in Isana Genetics’ Breeding Process


For Isana Genetics, terpene profiles are at the heart of their breeding process. Terpenes not only enhance the plant's aroma and flavor but also play a crucial role in shaping its effects. Isana’s five-step process to creating unique and memorable strains is built around carefully selecting and enhancing these terpene profiles.


Their terpene-focused breeding process is both art and science, involving a meticulous step-by-step approach:


  • Selection of Parent Strains: They start by selecting parent strains with distinct terpene profiles. Using lab results and sensory evaluations, they identify strains with terpene concentrations that will complement each other.

  • Breeding for Specific Characteristics: During the breeding process, they enhance particular terpenes while balancing flavors and aromas. For example, they might pair a limonene-rich strain with one high in myrcene to achieve a complex citrus profile.

  • Monitoring Terpene Development: As the new strains grow, they adjust light, temperature, and humidity to optimize terpene production and bring out the desired aromatic qualities.

  • Testing and Refinement: After cultivation, each new strain undergoes lab testing and sensory analysis to assess its terpene profile. If the aroma isn’t fully developed, they make further adjustments or continue breeding for refinement.

  • Creating a Unique Identity: The goal is to develop strains with a distinctive aroma and flavor that stand out in the market, giving each one a memorable identity.


Full macro view of a vibrant cannabis plant from Isana Genetics, featuring dense trichome coverage, bright orange pistils, and lush green leaves against a black background.

“Any journey is a blessing to meet people that share the passion for the plant,” Brent explains. “I would always approach and appreciate any grower’s efforts, as you can learn from anyone and everyone.”

Challenges and Rewards of Running a Cannabis Company


Running a cannabis company in today’s rapidly evolving market has its challenges. Like many startups, Isana Genetics has faced hurdles with funding and finding business partners who align with their vision. Brent and Kevin both recognize that resilience, humility, and adaptability are essential traits in this industry.



One of the most rewarding aspects of their work has been seeing how Isana Genetics has been accepted into the Maryland market.


“You have to be fit, humble, and malleable in this industry,” Brent notes, expressing gratitude for the community support they’ve received.

Connection to Global and Maryland-Specific Cannabis Culture


Staying connected to both global trends and the local Maryland cannabis culture is key for Isana Genetics. Brent and Kevin have decades of networking experience with people who share their passion for the plant. They continuously learn from these relationships and use their knowledge to refine their strains.

Alt Text: Close-up macro photo of cannabis pistils and trichomes from Isana Genetics, highlighting tall, frosty pistils and dense resin glands on a vibrant green background.

Whenever Isana uses these unique genetics, they make a point to pay homage to the original breeders. For Brent and Kevin, respecting the heritage of cannabis isn’t just an obligation—it’s a way to keep the creative culture of cannabis alive and thriving.


Through their work, they strive to push each other to higher standards. They aren’t competitive with each other; instead, they use their partnership to continually challenge and improve. Additionally, they’re always working on side projects outside of their formal breeding efforts, keeping their creativity and passion alive.


Macro photo of cannabis trichomes on a green leaf from Isana Genetics, capturing the resinous glandular structures that contribute to the plant’s potency and aromatic profile.

The Importance of Terpene Profiles in Developing Unique Aromas


Isana Genetics has built an extensive portfolio of cultivars over decades of breeding, and terpene profiles are integral to their process. They use their deep understanding of each cultivar’s terpene profile to create unique and memorable strains. By pulling new cultivars into their catalog, they enhance the flavor and complexity of their strains, often “cubing” a strain to highlight specific terpenes.




“We believe in bringing out the most of each cultivar,” Brent explains, underlining the dedication Isana has to showcase the plant’s true essence.


Opportunities in the Maryland Cannabis Market


The Maryland cannabis market presents both challenges and opportunities for Isana Genetics. One challenge they face is competing against well-established brands from the West Coast with massive marketing budgets. However, Brent and Kevin see this as a chance to define what Maryland cannabis can be.


By working with local legends, Isana can introduce unreleased cultivars and contribute to establishing Maryland’s unique cannabis identity. This dedication to local culture and innovation allows them to stand out, creating strains that reflect the tastes and preferences of the Maryland community.


The Origins of Isana Genetics


Brent and Kevin’s partnership goes back about 25 years. Both were cannabis business associates, with Kevin known for his “Kind Bud” that was always in demand. They reconnected in 2018 when Brent gifted Kevin some beans, leading to Sunday fireside sessions where they would sample each other’s cannabis and exchange ideas.


Once Maryland established its medical market, Brent envisioned Isana Genetics, combining his business acumen with Kevin’s skills in breeding and genetics. Together, they’ve built a collaborative partnership that allows each to leverage their strengths.

Full-view macro photo of a frosty cannabis bud from Isana Genetics, showcasing dense trichome coverage, vibrant orange pistils, and purple-tinged leaves against a black background.

Looking Ahead: The Future of Cannabis Genetics


Brent believes the future of cannabis genetics is broad, with many changes on the horizon as the industry matures. He expects to see some companies working with tissue culture, while others will continue with traditional clones. For Isana Genetics, innovation means creating new cultivars based on feedback from their loyal community.


As the Maryland market continues to evolve, Isana Genetics aims to form more partnerships, including exclusive collaborations with recent Social Equity awardees. Brent and Kevin are committed to attending cannabis events, promoting Isana Genetics, and sharing their knowledge and passion for cannabis with the community.


Conclusion

Isana Genetics is more than a cannabis brand; it’s a testament to the power of combining heritage and innovation. Brent and Kevin’s commitment to staying true to the plant, their focus on terpene profiles, and their respect for original breeders make them a standout in Maryland’s cannabis market. Through Isana Genetics, they are shaping the future of cannabis connoisseurship, creating strains that resonate with both tradition and progress.


For those looking to deepen their knowledge or explore new flavors, Isana Genetics offers a blend of authenticity, expertise, and a forward-thinking approach that reflects the true artistry of cannabis.


Extreme macro photo of a cannabis bud from Isana Genetics, highlighting frosty trichomes, deep purple hues, and vibrant orange pistils in intricate detail.

Key Takeaways
  • Blend of Heritage and Innovation: Isana Genetics combines traditional cannabis genetics with new-school innovation, offering unique strains that honor the plant's legacy while embracing modern advancements.

  • Terpene-Driven Breeding Process: Their five-step breeding process focuses on selecting parent strains with distinctive terpene profiles, optimizing growth conditions, and refining each strain to create a unique sensory experience.

  • Commitment to Quality and Authenticity: Brent and Kevin prioritize staying authentic to the plant and themselves, selecting strains that reflect true cannabis qualities and respecting the original breeders in their creations.

  • Deep Industry Knowledge and Community Connections: Decades of networking allow Isana Genetics to remain connected to global trends while staying grounded in Maryland’s cannabis culture, ensuring their strains resonate with the local community.

  • Overcoming Industry Challenges: Isana Genetics has faced challenges with funding and competition from larger brands, but their resilience and passion have earned them a place in Maryland's cannabis market.

  • A Vision for Maryland Cannabis: With a focus on local culture and innovation, Isana Genetics is helping define Maryland’s cannabis identity, bringing unique strains to the community and building partnerships that reflect their values.




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